Caspase-8 (CASP8 or CAP4) Antibody
BiCell Scientific
SKU:10308-50UL
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Biological Background
When you need to explore Caspase-8 with attention to cellular organization, this antibody provides a focused option. Caspase-8 is a protein of interest for mapping abundance changes across conditions and cell states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking Caspase-8 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Use in the Laboratory
Temporal sampling and matched controls can improve interpretation when expression is dynamic. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- interpretation alongside orthogonal readouts
- cross-sample normalization strategies
- subcellular compartment mapping
Version Notes
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
If your study spans multiple model systems, it can help to define a shared reference condition for Caspase-8 so cross-sample contrasts stay meaningful.
If your study spans multiple model systems, it can help to define a shared reference condition for Caspase-8 so cross-sample contrasts stay meaningful.
The regular format version supports deeper biological narratives around Caspase-8 without overcomplicating setup.
- Targets:
- CASP8
- Research Area:
- Apoptosis
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse Caspase-8 protein (p10 subunit)
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q14790
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C