CaSR Antibody
BiCell Scientific
SKU:50102-50UL
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Protein Function
Bring CaSR into view to assess changes across conditions. CaSR is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Look for shifts in distribution that track with phenotype changes.
Following CaSR across perturbations can help separate expression effects from compartment shifts.
Experimental Applications
Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- condition-to-condition comparisons with matched controls
- localization shifts between cytoplasm, membrane, and nucleus
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
Workflow Perspective
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
When interpreting CaSR, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CaSR patterns can be compared across experiments without guesswork.
Choose the regular format option when you want CaSR results aligned to your sample format.
- Targets:
- CASR
- Research Area:
- Cardiovascular • Cell Signaling • Endocrinology • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of mouse CaSR protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P41180
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 82.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C