CCG-1423
Selleck Chemicals
SKU:S7719-10MG
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CCG-1423 is an inhibitor of Rho GTPases used in studies of target-focused biology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to annotated target biology and downstream cellular responses in cancer, cell cycle, and cell signaling models.
By inhibiting Rho GTPases, CCG-1423 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Rho GTPases
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in cancer, cell cycle, and cell signaling models
- Combination studies with orthogonal perturbagens
Overall, CCG-1423 is appropriate when a defined chemical perturbant is needed to connect Rho GTPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Rho GTPases
- Target Class:
- Other
- Research Area:
- Cancer • Cell Cycle • Cell Signaling
- CAS No.:
- 285986-88-1
- Molecular Weight:
- 454.75
- Formula:
- C₁₈H₁₃ClF₆N₂O₃
- SMILES:
- CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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