CCG-222740

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Selleck Chemicals

S6673-2MG

€175,00 EUR
€175,00 EUR
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CCG-222740 is an inhibitor of Rho GTPases used in studies of target-focused biology. In practice, this places the compound in experiments that measure annotated target biology and downstream cellular responses in cancer, cell cycle, and cell signaling models.

By inhibiting Rho GTPases, CCG-222740 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Rho GTPases
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cell cycle, and cell signaling models
  • Combination studies with orthogonal perturbagens

Overall, CCG-222740 is appropriate when a defined chemical perturbant is needed to connect Rho GTPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Rho GTPases
Target Class:
Other
Research Area:
Cancer • Cell Cycle • Cell Signaling
CAS No.:
1922098-69-8
Molecular Weight:
444.86
Formula:
C₂₃H₁₉ClF₂N₂O₃
SMILES:
C1C(CN(CC1(F)F)C(=O)C2=CC=CC(=C2)C3=CC=CO3)C(=O)NC4=CC=C(C=C4)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.