CCR5 (CD195) Antibody
BiCell Scientific
SKU:64135-50UL
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Biological Background
When control selection matters, this antibody helps you characterize CCR5 in a structured study. CCR5 is a receptor-linked protein that can influence cell communication and downstream signaling. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol CD195.
Use in the Laboratory
Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Time course design can be decisive when regulation is transient or compartment dependent.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- panel-based interpretation with additional lineage markers
- activation-dependent changes across stimulation conditions
- comparisons across differentiation or polarization states
Version Notes
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Predefine decision rules for excluding outliers so analysis remains transparent.
If your study spans multiple model systems, it can help to define a shared reference condition for CCR5 so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR5 patterns can be compared across experiments without guesswork.
Use the regular format option to keep CCR5 analysis aligned with planned contrasts and endpoints.
- Targets:
- CCR5
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse CCR5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51681
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 80% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C