CCR6 (CD196) Antibody
BiCell Scientific
SKU:64136-50UL
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Scientific Overview
This antibody enables you to examine CCR6 (CD196) with a direct, biology-first readout. CCR6 is a receptor-linked protein that can influence cell communication and downstream signaling. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol CD196.
Research Relevance
Immune markers are often interpreted alongside a panel of complementary targets to improve population resolution. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- assessment of surface versus internalized pools
- panel-based interpretation with additional lineage markers
- comparisons across differentiation or polarization states
- activation-dependent changes across stimulation conditions
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting CCR6, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR6 patterns can be compared across experiments without guesswork.
With a clear focus on CCR6 (CD196), this regular format option fits streamlined studies and fast iteration.
- Targets:
- CCR6
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of mouse CCR6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51684
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 88.2% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C