CCR6 (CD196) Antibody - FFPE Validated

Protein Function

For consistent comparison across experiments, use this antibody to examine CCR6 (CD196) with a repeatable workflow. CCR6 is a surface or signaling marker used to characterize immune cell subsets and activation states. Use matched handling so differences reflect biology rather than processing.

In some datasets and protocols, it is referenced by the gene symbol CD196.

Experimental Applications

Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.

Common experimental questions that benefit from target tracking include:

• panel-based interpretation with additional lineage markers
• activation-dependent changes across stimulation conditions
• assessment of surface versus internalized pools
• comparisons across differentiation or polarization states

Workflow Perspective

For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.

For challenging targets, pairing CCR6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

For multi-run studies, the fixed-section option helps keep CCR6 (CD196) trends comparable from experiment to experiment.