CCR7 (CD197) Antibody
BiCell Scientific
SKU:64137-50UL
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About the Target
When you need to characterize CCR7 with attention to cellular organization, this antibody provides a focused option. CCR7 is a receptor-linked protein that can influence cell communication and downstream signaling. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring CCR7 alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- activation-dependent changes across stimulation conditions
- assessment of surface versus internalized pools
- comparisons across differentiation or polarization states
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing CCR7 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR7 patterns can be compared across experiments without guesswork.
Use the regular format variant when your project demands CCR7 readouts that respect preparation constraints.
- Targets:
- CCR7
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal cytoplasmic region of mouse CCR7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P32248
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C