CCT241533 hydrochloride
Selleck Chemicals
SKU:E1653-1MG
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CCT241533 hydrochloride is an inhibitor of CHK used in studies of DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control in cancer, cell cycle, and cell signaling models.
By inhibiting CHK, CCT241533 hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving CHK
- Pathway perturbation studies connected to DNA Damage Response
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, CCT241533 hydrochloride is appropriate when a defined chemical perturbant is needed to connect CHK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- CHK
- Target Class:
- Kinase
- Pathways:
- DNA Damage Response
- Research Area:
- Cancer • Cell Cycle • Cell Signaling • DNA Damage / Repair
- CAS No.:
- 1431697-96-9
- Molecular Weight:
- 478.95
- Formula:
- C₂₃H₂₇FN₄O₄·ClH
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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