CD2AP Antibody
BiCell Scientific
SKU:00173-50UL
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About the Target
This antibody is suited for researchers who want to evaluate CD2AP and relate it to cell-state biology. CD2AP is a structural regulator of intercellular boundaries and tissue architecture. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking CD2AP can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Podocyte biology studies may assess this target when examining slit-diaphragm organization and cytoskeletal coupling.
Consider these angles when interpreting target-level changes:
- subcellular redistribution at contact sites versus cytoplasm
- changes in complex assembly with scaffold or adaptor proteins
- co-localization patterns with cytoskeletal elements
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing CD2AP measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing CD2AP measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
As you refine hypotheses around CD2AP, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- CD2AP
- Research Area:
- Cell Signaling • Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of mouse CD2AP protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y5K6
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 82.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C