CDDO-Im (RTA-403)

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Selleck Chemicals

S9723-5MG

€185,00 EUR
€185,00 EUR
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CDDO-Im (RTA-403) is an activator of NRF2 and PPAR gamma and related targets used in studies of Oxidative Stress Response and Hormone Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses and ligand-dependent transcriptional programs and endocrine regulation in endocrinology, immunology, and inflammation models.

By activating NRF2 and PPAR gamma and related targets, CDDO-Im (RTA-403) can be used to examine redox signaling, ROS handling, and antioxidant defenses and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NRF2 and PPAR gamma and related targets
  • Pathway perturbation studies connected to Oxidative Stress Response and Hormone Signaling and related signaling programs
  • Gain-of-function pathway-activation studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, CDDO-Im (RTA-403) is appropriate when a defined chemical perturbant is needed to connect NRF2 and PPAR gamma and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NRF2 • PPAR gamma • PPAR alpha
Target Class:
Nuclear Receptor
Pathways:
Oxidative Stress Response • Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Immunology • Inflammation • Metabolism
CAS No.:
443104-02-7
Molecular Weight:
541.72
SMILES:
CC1(C)CCC2(CCC3(C)C(C2C1)C(=O)C=C4C5(C)C=C(C#N)C(=O)C(C)(C)C5CCC34C)C(=O)[N]6C=CN=C6
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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