CELSR2 (CDHF10 or Flamingo1) Antibody - FFPE Validated
BiCell Scientific
SKU:50802-FFPE-50UL
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About the Target
When you need to analyze CELSR2 with attention to cellular organization, this antibody provides a focused option. CELSR2 is a structural regulator of intercellular boundaries and tissue architecture. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CDHF10.
Research Context
Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- changes in complex assembly with scaffold or adaptor proteins
- comparative profiling across cell states or perturbations
- co-localization patterns with cytoskeletal elements
Variant Considerations
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting CELSR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting CELSR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
As you refine hypotheses around CELSR2, the fixed-section format helps keep conclusions tied to preparation context.
- Targets:
- CELSR2
- Research Area:
- Cell Signaling • Developmental Biology • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal region of human CELSR2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9HCU4
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.