CELSR2 (CDHF10 or Flamingo1) Antibody - Western Blot Validated

Scientific Overview

Bring CELSR2 into view to assess changes across conditions. CELSR2 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol CDHF10.

Research Relevance

Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.

When building a narrative around the target, it helps to track:

• subcellular redistribution at contact sites versus cytoplasm
• changes in complex assembly with scaffold or adaptor proteins
• co-localization patterns with cytoskeletal elements
• comparative profiling across cell states or perturbations

Application-Specific Context

If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CELSR2 patterns can be compared across experiments without guesswork.

With a clear focus on CELSR2, this denaturing-format option fits streamlined studies and fast iteration.