CELSR3 (CDHF11 or FMI1) Antibody

Scientific Overview

This antibody enables you to analyze CELSR3 with a direct, biology-first readout. CELSR3 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Focus on trends across conditions rather than single-point snapshots.

In some datasets and protocols, it is referenced by the gene symbol FMI1.

Research Relevance

Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

When building a narrative around the target, it helps to track:

• subcellular redistribution at contact sites versus cytoplasm
• changes in complex assembly with scaffold or adaptor proteins
• comparative profiling across cell states or perturbations
• co-localization patterns with cytoskeletal elements

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

When interpreting CELSR3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

With a clear focus on CELSR3, this regular format option fits streamlined studies and fast iteration.