CEP-33779

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Selleck Chemicals

S2806-5MG

€265,00 EUR
€265,00 EUR
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CEP-33779 is an inhibitor of JAK2 used in studies of JAK-STAT Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-responsive transcriptional signaling and immune regulation in cancer, cell signaling, and immunology models.

By inhibiting JAK2, CEP-33779 can be used to examine cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving JAK2
  • Pathway perturbation studies connected to JAK-STAT Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, CEP-33779 is appropriate when a defined chemical perturbant is needed to connect JAK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
JAK2
Target Class:
Kinase
Pathways:
JAK-STAT Signaling
Research Area:
Cancer • Cell Signaling • Immunology • Inflammation
CAS No.:
1257704-57-6
Molecular Weight:
462.57
Formula:
C₂₄H₂₆N₆O₂S
SMILES:
CN1CCN(CC1)C2=CC=CC(=C2)NC3=NN4C=CC=C(C4=N3)C5=CC=C(C=C5)S(=O)(=O)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.