CEP164 (NPHP15) Antibody

Scientific Overview

This antibody helps you examine CEP164 while keeping condition-to-condition contrasts straightforward. CEP164 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.

In some datasets and protocols, it is referenced by the gene symbol NPHP15.

Research Relevance

Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

• signal enrichment at basal bodies versus cytoplasm
• cell-cycle linked differences in localization
• co-occurrence with intraflagellar transport markers
• changes in cilia incidence or apparent length in perturbation studies

Application-Specific Context

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.

For challenging targets, pairing CEP164 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

For multi-run studies, the regular format option helps keep CEP164 trends comparable from experiment to experiment.