CEP57 Antibody
BiCell Scientific
SKU:01073-50UL
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Protein Function
This antibody supports efforts to characterize CEP57 and interpret it within interaction networks. CEP57 is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking CEP57 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Disruption of intraflagellar transport or basal body function can produce distinct localization signatures. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- co-occurrence with intraflagellar transport markers
- signal enrichment at basal bodies versus cytoplasm
- cell-cycle linked differences in localization
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
When interpreting CEP57, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing CEP57 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format version to relate CEP57 behavior to upstream cues and downstream consequences.
- Targets:
- CEP57
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of mouse CEP57 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q86XR8
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C