CEP63 Antibody - FFPE Validated
BiCell Scientific
SKU:01075-FFPE-50UL
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About the Target
When you need to examine CEP63 with attention to cellular organization, this antibody provides a focused option. CEP63 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring CEP63 alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Ciliary proteins are frequently assessed in relation to cell-cycle stage, serum conditions, and differentiation cues. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- cell-cycle linked differences in localization
- co-occurrence with intraflagellar transport markers
- signal enrichment at basal bodies versus cytoplasm
Variant Considerations
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting CEP63, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
When interpreting CEP63, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The fixed-section version supports deeper biological narratives around CEP63 without overcomplicating setup.
- Targets:
- CEP63
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the N-terminal region of mouse CEP63 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q96MT8
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C