CEP70 Antibody
BiCell Scientific
SKU:01076-50UL
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Scientific Overview
Use this antibody to characterize CEP70 in your model system. CEP70 is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Look for shifts in distribution that track with phenotype changes.
Following CEP70 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- co-occurrence with intraflagellar transport markers
- changes in cilia incidence or apparent length in perturbation studies
- signal enrichment at basal bodies versus cytoplasm
- cell-cycle linked differences in localization
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for CEP70 so cross-sample contrasts stay meaningful.
For challenging targets, pairing CEP70 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Choose the regular format option when you want CEP70 results aligned to your sample format.
- Targets:
- CEP70
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse CEP70 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8NHQ1
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C