CEP70 Antibody

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BiCell Scientific

SKU:01076-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

Use this antibody to characterize CEP70 in your model system. CEP70 is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Look for shifts in distribution that track with phenotype changes.

Following CEP70 across perturbations can help separate expression effects from compartment shifts.

Research Relevance

Quantitative comparisons often rely on consistent imaging parameters and clear inclusion criteria for ciliated cells. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

  • co-occurrence with intraflagellar transport markers
  • changes in cilia incidence or apparent length in perturbation studies
  • signal enrichment at basal bodies versus cytoplasm
  • cell-cycle linked differences in localization

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

If your study spans multiple model systems, it can help to define a shared reference condition for CEP70 so cross-sample contrasts stay meaningful.

For challenging targets, pairing CEP70 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

Choose the regular format option when you want CEP70 results aligned to your sample format.

Targets:
CEP70
Research Area:
Cell Cycle • Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the C-terminal region of mouse CEP70 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q8NHQ1
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 93.8% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C