CFTRinh-172

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Selleck Chemicals

S7139-10MG

€144,00 EUR
€144,00 EUR
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CFTRinh-172 is an inhibitor of CFTR used in studies of ion-channel pharmacology. It is especially relevant in cell signaling models, where defined compound exposure can be linked to ion conductance, membrane potential, and electrophysiological responses. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting CFTR, CFTRinh-172 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CFTR
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cell signaling models

Overall, CFTRinh-172 is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CFTR
Target Class:
Ion Channel
Research Area:
Cell Signaling
CAS No.:
307510-92-5
Molecular Weight:
409.4
Formula:
C₁₈H₁₀F₃NO₃S₂
SMILES:
C1=CC(=CC(=C1)N2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S)C(F)(F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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