CGP-37157
Selleck Chemicals
SKU:E0002-5MG
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CGP-37157 is an inhibitor of NCX used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in cardiovascular and cell signaling models.
By inhibiting NCX, CGP-37157 can be used to examine calcium flux, excitability, and secretion-linked signaling. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving NCX
- Pathway perturbation studies connected to Calcium Signaling
- Concentration-response inhibition and target-dependence studies
- Transport, uptake/efflux, and permeability assays
Overall, CGP-37157 is appropriate when a defined chemical perturbant is needed to connect NCX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- NCX
- Target Class:
- Transporter
- Pathways:
- Calcium Signaling
- Research Area:
- Cardiovascular • Cell Signaling
- CAS No.:
- 75450-34-9
- Molecular Weight:
- 324.22
- Formula:
- C₁₅H₁₁Cl₂NOS
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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