CGP52432

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Selleck Chemicals

S0303-5MG

€144,00 EUR
€144,00 EUR
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CGP52432 is an antagonist of GABA Receptors used in studies of Neurotransmission. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.

By blocking GABA Receptors, CGP52432 can be used to examine synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GABA Receptors
  • Pathway perturbation studies connected to Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • Phenotypic profiling in neuroscience models

Overall, CGP52432 is appropriate when a defined chemical perturbant is needed to connect GABA Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GABA Receptors
Target Class:
Other
Pathways:
Neurotransmission
Research Area:
Neuroscience
CAS No.:
139667-74-6
Molecular Weight:
384.24
Formula:
C₁₅H₂₄Cl₂NO₄P
SMILES:
CCOC(OCC)P(=O)(CCCNCC1=CC(=C(C=C1)Cl)Cl)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.