CGS 21680 HCl

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Selleck Chemicals

SKU:S2153-5MG

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CGS 21680 HCl is an agonist of Adenosine Receptors used in studies of GPCR Signaling. It is especially relevant in cardiovascular and inflammation models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics.

By activating Adenosine Receptors, CGS 21680 HCl can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Adenosine Receptors
  • Pathway perturbation studies connected to GPCR Signaling
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, CGS 21680 HCl is appropriate when a defined chemical perturbant is needed to connect Adenosine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Adenosine Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cardiovascular • Inflammation
CAS No.:
124431-80-7
Molecular Weight:
535.98
Formula:
C₂₃H₂₉N₇O₆·HCl
SMILES:
CCNC(=O)C1C(C(C(O1)N2C=NC3=C(N=C(N=C32)NCCC4=CC=C(C=C4)CCC(=O)O)N)O)O.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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