CH5132799
Selleck Chemicals
SKU:S2699-5MG
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CH5132799 is an inhibitor of PI3K and PI3K beta and related targets used in studies of PI3K-Akt-mTOR Signaling. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs in cancer, cell signaling, and immunology models.
By inhibiting PI3K and PI3K beta and related targets, CH5132799 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving PI3K and PI3K beta and related targets
- Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, CH5132799 is appropriate when a defined chemical perturbant is needed to connect PI3K and PI3K beta and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- PI3K • PI3K beta • PI3K alpha • PI3K delta
- Target Class:
- Kinase
- Pathways:
- PI3K-Akt-mTOR Signaling
- Research Area:
- Cancer • Cell Signaling • Immunology • Metabolism
- CAS No.:
- 1007207-67-1
- Molecular Weight:
- 377.42
- Formula:
- C₁₅H₁₉N₇O₃S
- SMILES:
- CS(=O)(=O)N1CCC2=C(N=C(N=C21)N3CCOCC3)C4=CN=C(N=C4)N
- InChIKey:
- JEGHXKRHKHPBJD-UHFFFAOYSA-N
- PubChem:
- 49784945
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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