Chloroquine dihydrochloride

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Selleck Chemicals

SKU:E8307-5MG

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Chloroquine dihydrochloride is an inhibitor of Autophagy used in studies of Autophagy. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to autophagic flux, lysosomal turnover, and stress adaptation in autophagy models.

By inhibiting Autophagy, Chloroquine dihydrochloride can be used to examine autophagic flux, lysosomal turnover, and stress adaptation. The autophagy modulator annotation adds relevance to autophagy-flux and lysosomal-response studies, together with downstream-response mapping in the same experimental setting. In autophagy models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Autophagy
  • Pathway perturbation studies connected to Autophagy
  • Concentration-response inhibition and target-dependence studies
  • Autophagy-flux and lysosomal-response studies

Overall, Chloroquine dihydrochloride is appropriate when a defined chemical perturbant is needed to connect Autophagy with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Autophagy
Target Class:
Autophagy Modulator
Pathways:
Autophagy
Research Area:
Autophagy
CAS No.:
3545-67-3
Molecular Weight:
392.79
Formula:
C₁₈H₂₆ClN₃·2ClH
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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