Chlorpromazine HCl
Selleck Chemicals
SKU:S2456-50MG
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Chlorpromazine HCl is an inhibitor of Dopamine Receptors and Potassium Channels used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in cardiovascular and neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.
By inhibiting Dopamine Receptors and Potassium Channels, Chlorpromazine HCl can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Dopamine Receptors and Potassium Channels
- Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
- Concentration-response inhibition and target-dependence studies
- GPCR pharmacology, ligand-binding, and signaling assays
Overall, Chlorpromazine HCl is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors and Potassium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Dopamine Receptors • Potassium Channels
- Target Class:
- GPCR
- Pathways:
- GPCR Signaling • Neurotransmission
- Research Area:
- Cardiovascular • Neuroscience
- CAS No.:
- 69-09-0
- Molecular Weight:
- 355.33
- Formula:
- C₁₇H₁₉ClN₂S·HCl
- SMILES:
- CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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