CHRNA3 (NACHRA3) Antibody

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BiCell Scientific

SKU:15183-50UL

Regular price €335,00 EUR
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Blocking Peptide
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Scientific Overview

This antibody enables you to examine CHRNA3 (NACHRA3) with a direct, biology-first readout. CHRNA3 is a membrane protein linked to solute movement and gradient maintenance. Focus on trends across conditions rather than single-point snapshots.

Following CHRNA3 across perturbations can help separate expression effects from compartment shifts.

Research Relevance

Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

When building a narrative around the target, it helps to track:

  • patterns consistent with apical or basolateral sorting
  • surface versus intracellular pool distribution
  • stimulus-dependent trafficking and turnover
  • relative abundance across engineered constructs

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

For challenging targets, pairing CHRNA3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

With a clear focus on CHRNA3 (NACHRA3), this regular format option fits streamlined studies and fast iteration.

Targets:
CHRNA3
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the N-terminal extracellular region of mouse CHRNA3 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P32297
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 78.6% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.