CHRNA4 (NACHRA4) Antibody
BiCell Scientific
SKU:15184-50UL
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About the Target
This antibody is suited for researchers who want to evaluate CHRNA4 (NACHRA4) and relate it to cell-state biology. CHRNA4 is a membrane-embedded regulator of ionic or osmotic balance in cells. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol NACHRA4.
Research Context
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CHRNA4 patterns can be compared across experiments without guesswork.
If your study spans multiple model systems, it can help to define a shared reference condition for CHRNA4 so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands CHRNA4 (NACHRA4) readouts that respect preparation constraints.
- Targets:
- CHRNA4
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse CHRNA4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P43681
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 92.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C