CHRNB1 (ACHRB) Antibody
BiCell Scientific
SKU:15191-50UL
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Scientific Overview
When control selection matters, this antibody helps you examine CHRNB1 (ACHRB) in a structured study. CHRNB1 is a channel or transporter associated with regulated flux across cellular membranes. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
In some datasets and protocols, it is referenced by the gene symbol ACHRB.
Research Relevance
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Time course design can be decisive when regulation is transient or compartment dependent.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- patterns consistent with apical or basolateral sorting
Application-Specific Context
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. Align controls to the expected direction of change to support confident interpretation.
For challenging targets, pairing CHRNB1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format option to keep CHRNB1 (ACHRB) analysis aligned with planned contrasts and endpoints.
- Targets:
- CHRNB1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of human CHRNB1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P11230
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C