Chromium picolinate

1 1

Selleck Chemicals

S6443-25MG

€95,00 EUR
€95,00 EUR
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Chromium picolinate is a modulator of IGF-1R used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant in cancer, cell signaling, and metabolism models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs.

By modulating IGF-1R, Chromium picolinate can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving IGF-1R
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
  • Context-dependent response profiling and mechanism comparison
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Chromium picolinate is appropriate when a defined chemical perturbant is needed to connect IGF-1R with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
IGF-1R
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling
Research Area:
Cancer • Cell Signaling • Metabolism
CAS No.:
14639-25-9
Molecular Weight:
418.3
Formula:
C₁₈H₁₂CrN₃O₆
SMILES:
C1=CC=NC(=C1)C(=O)[O-].C1=CC=NC(=C1)C(=O)[O-].C1=CC=NC(=C1)C(=O)[O-].[Cr+3]
InChIKey:
CBDQOLKNTOMMTL-UHFFFAOYSA-K
PubChem:
625469
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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