Cilengitide (EMD 121974)

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Selleck Chemicals

S6387-5MG

€144,00 EUR
€144,00 EUR
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Cilengitide (EMD 121974) is an inhibitor of Integrins used in studies of target-focused biology. It is especially relevant in angiogenesis and cancer models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.

By inhibiting Integrins, Cilengitide (EMD 121974) can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In angiogenesis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Integrins
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in angiogenesis and cancer models
  • Combination studies with orthogonal perturbagens

Overall, Cilengitide (EMD 121974) is appropriate when a defined chemical perturbant is needed to connect Integrins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Integrins
Target Class:
Other
Research Area:
Angiogenesis • Cancer
CAS No.:
188968-51-6
Molecular Weight:
588.66
Formula:
C₂₇H₄₀N₈O₇
SMILES:
CC(C)C1N(C)C(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(CCCNC(N)=N)NC1=O
InChIKey:
AMLYAMJWYAIXIA-UHFFFAOYSA-N
PubChem:
176873
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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