Cinacalcet (AMG-073)HCl

1 1

Selleck Chemicals

S1260-10MG

€117,00 EUR
€117,00 EUR
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Cinacalcet (AMG-073)HCl is an activator linked to GPCR Signaling and related pathway-oriented research. It is especially relevant in endocrinology models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics.

The pathway annotation connects Cinacalcet (AMG-073)HCl to GPCR Signaling, supporting experiments that monitor receptor-driven second-messenger signaling and desensitization dynamics across biochemical, cellular, or phenotypic assay formats. This context is compatible with ligand-response, cAMP, calcium-flux, and receptor-pharmacology assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to GPCR Signaling
  • Gain-of-function pathway-activation studies
  • Phenotypic profiling in endocrinology models
  • Combination studies with orthogonal perturbagens

Overall, Cinacalcet (AMG-073)HCl is well suited to pathway-oriented studies that need a defined compound input for GPCR Signaling readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
GPCR Signaling
Research Area:
Endocrinology
CAS No.:
364782-34-3
Molecular Weight:
393.87
Formula:
C₂₂H₂₂F₃N·HCl
SMILES:
CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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