Ciprofibrate

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Selleck Chemicals

SKU:S2665-25MG

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Ciprofibrate is an agonist of PPAR used in studies of DNA Damage Response and Hormone Signaling and related signaling programs. It is especially relevant in cancer, dna damage / repair, and endocrinology models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and ligand-dependent transcriptional programs and endocrine regulation.

By activating PPAR, Ciprofibrate can be used to examine checkpoint activation, DNA repair, and genome-stability control and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR
  • Pathway perturbation studies connected to DNA Damage Response and Hormone Signaling and related signaling programs
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Ciprofibrate is appropriate when a defined chemical perturbant is needed to connect PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR
Target Class:
Nuclear Receptor
Pathways:
DNA Damage Response • Hormone Signaling • Metabolic Signaling
Research Area:
Cancer • DNA Damage / Repair • Endocrinology • Metabolism
CAS No.:
52214-84-3
Molecular Weight:
289.15
Formula:
C₁₃H₁₄Cl₂O₃
SMILES:
CC(C)(C(=O)O)OC1=CC=C(C=C1)C2CC2(Cl)Cl
InChIKey:
KPSRODZRAIWAKH-UHFFFAOYSA-N
PubChem:
17397655
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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