Claudin-17 (CLDN17) Antibody
BiCell Scientific
SKU:00217-50UL
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Protein Function
Bring Claudin-17 (CLDN17) into view to analyze changes across conditions. Claudin-17 is a membrane-associated component that helps organize cell-cell contacts and polarity. Look for shifts in distribution that track with phenotype changes.
Monitoring Claudin-17 alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
In cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- co-localization patterns with cytoskeletal elements
- changes in complex assembly with scaffold or adaptor proteins
- subcellular redistribution at contact sites versus cytoplasm
- comparative profiling across cell states or perturbations
Workflow Perspective
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-17 patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-17 patterns can be compared across experiments without guesswork.
With a clear focus on Claudin-17 (CLDN17), this regular format option fits streamlined studies and fast iteration.
- Targets:
- CLDN17
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal intracellular region of mouse Claudin-17 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P56750
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 56.2% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C