Claudin-9 (CLDN9) Antibody - FFPE Validated
BiCell Scientific
SKU:00209-FFPE-50UL
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About the Target
Designed to help you characterize Claudin-9 (CLDN9), this antibody supports studies where protein context matters. Claudin-9 is a membrane-associated component that helps organize cell-cell contacts and polarity. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CLDN9.
Research Context
Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- comparative profiling across cell states or perturbations
- co-localization patterns with cytoskeletal elements
- changes in complex assembly with scaffold or adaptor proteins
Variant Considerations
This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Claudin-9, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing Claudin-9 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the fixed-section variant when your project demands Claudin-9 (CLDN9) readouts that respect preparation constraints.
- Targets:
- CLDN9
- Research Area:
- Developmental Biology • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human Claudin-9 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O95484
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C