Clemastine (HS-592)Fumarate

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Selleck Chemicals

S1847-50MG

€144,00 EUR
€144,00 EUR
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Clemastine (HS-592)Fumarate is an antagonist of MTOR and Histamine Receptors used in studies of PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.

By blocking MTOR and Histamine Receptors, Clemastine (HS-592)Fumarate can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MTOR and Histamine Receptors
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Clemastine (HS-592)Fumarate is appropriate when a defined chemical perturbant is needed to connect MTOR and Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MTOR • Histamine Receptors
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • Autophagy • GPCR Signaling
Research Area:
Autophagy • Cancer • Cell Signaling • Inflammation
CAS No.:
14976-57-9
Molecular Weight:
459.96
Formula:
C₂₁H₂₆ClNO·C₄H₄O₄
SMILES:
CC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCC3CCCN3C.C(=CC(=O)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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