Clozapine N-oxide (CNO chemical)

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Selleck Chemicals

S6887-5MG

€144,00 EUR
€144,00 EUR
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Clozapine N-oxide (CNO chemical) is an agonist of Dopamine Receptors and AChR used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in neuroscience models.

By activating Dopamine Receptors and AChR, Clozapine N-oxide (CNO chemical) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Dopamine Receptors and AChR
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Clozapine N-oxide (CNO chemical) is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors and AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Dopamine Receptors • AChR
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Neuroscience
CAS No.:
34233-69-7
Molecular Weight:
342.82
Formula:
C₁₈H₁₉ClN₄O
SMILES:
C[N+]1([O-])CCN(CC1)C2=NC3=C(NC4=CC=CC=C24)C=CC(=C3)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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