CLPP (PRLTS3 or DFNB81) Antibody - FFPE Validated
BiCell Scientific
SKU:54225-FFPE-50UL
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Scientific Overview
This antibody is suited for researchers who want to explore CLPP and relate it to cell-state biology. CLPP is a cellular protein that can be tracked to understand expression patterns and compartmental behavior. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring CLPP alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
Temporal sampling and matched controls can improve interpretation when expression is dynamic. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- subcellular compartment mapping
- interpretation alongside orthogonal readouts
- cross-sample normalization strategies
Application-Specific Context
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CLPP patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CLPP patterns can be compared across experiments without guesswork.
Use the fixed-section variant when your project demands CLPP readouts that respect preparation constraints.
- Targets:
- CLPP
- Research Area:
- Metabolism
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal region of human CLPP protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q16740
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C