Connexin-36 (Cx36 or Gjd2) Antibody - FFPE Validated
BiCell Scientific
SKU:00403-FFPE-50UL
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Protein Function
This antibody supports efforts to evaluate Connexin-36 and interpret it within interaction networks. Connexin-36 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking Connexin-36 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy.
Common experimental questions that benefit from target tracking include:
- changes in complex assembly with scaffold or adaptor proteins
- co-localization patterns with cytoskeletal elements
- subcellular redistribution at contact sites versus cytoplasm
Workflow Perspective
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Connexin-36 patterns can be compared across experiments without guesswork.
Choose the fixed-section format to study Connexin-36 in a way that stays anchored to pathway logic.
- Targets:
- GJD2
- Research Area:
- Developmental Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human Connexin-36 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UKL4
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C