Coptisine chloride

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Selleck Chemicals

S5249-5MG

€114,00 EUR
€114,00 EUR
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Coptisine chloride is an inhibitor of IDO1 and TDO used in studies of Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses in cancer, immunology, and infectious disease models.

By inhibiting IDO1 and TDO, Coptisine chloride can be used to examine cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving IDO1 and TDO
  • Pathway perturbation studies connected to Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Coptisine chloride is appropriate when a defined chemical perturbant is needed to connect IDO1 and TDO with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
IDO1 • TDO
Target Class:
Enzyme
Pathways:
Immune Signaling
Research Area:
Cancer • Immunology • Infectious Disease • Metabolism
CAS No.:
6020-18-4
Molecular Weight:
355.77
Formula:
C₁₉H₁₄NO₄·Cl
SMILES:
C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6.[Cl-]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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