CX3CR1 (CCRL1 or GPR13) Antibody - FFPE Validated

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BiCell Scientific

SKU:64161-FFPE-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

This antibody helps you explore CX3CR1 (CCRL1) while keeping condition-to-condition contrasts straightforward. CX3CR1 is a cellular protein that can be tracked to understand expression patterns and compartmental behavior. Use matched handling so differences reflect biology rather than processing.

In some datasets and protocols, it is referenced by the gene symbol CCRL1.

Research Relevance

In many projects, target-level measurements help link perturbations to downstream phenotypes. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.

When building a narrative around the target, it helps to track:

  • cross-sample normalization strategies
  • baseline versus stimulated condition comparisons
  • subcellular compartment mapping
  • interpretation alongside orthogonal readouts

Application-Specific Context

Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.

When interpreting CX3CR1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For multi-run studies, the fixed-section option helps keep CX3CR1 (CCRL1) trends comparable from experiment to experiment.

Targets:
CX3CR1
Research Area:
Cell Signaling • Immunology • Inflammation
Application:
IHC-P
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse CX3CR1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P49238
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 66.7% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C