CXCR2 (CD182 or IL8RB) Antibody

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BiCell Scientific

SKU:64152-50UL

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Size
Blocking Peptide
Quantity
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About the Target

Bring CXCR2 (CD182) into view to analyze changes across conditions. CXCR2 is a surface or signaling marker used to characterize immune cell subsets and activation states. Focus on trends across conditions rather than single-point snapshots.

In some datasets and protocols, it is referenced by the gene symbol CD182.

Research Context

Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Consider these angles when interpreting target-level changes:

  • panel-based interpretation with additional lineage markers
  • activation-dependent changes across stimulation conditions
  • assessment of surface versus internalized pools
  • comparisons across differentiation or polarization states

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

When interpreting CXCR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For challenging targets, pairing CXCR2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

With a clear focus on CXCR2 (CD182), this regular format option fits streamlined studies and fast iteration.

Targets:
CXCR2
Research Area:
Cell Signaling • Developmental Biology • Immunology • Inflammation
Application:
IF • IHC • WB
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the N-terminal extracellular region of mouse CXCR2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P25025
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 31.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C