CXCR2 (CD182 or IL8RB) Antibody - Western Blot Validated

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BiCell Scientific

SKU:64152-WB-50UL

Regular price €530,00 EUR
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Blocking Peptide
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Protein Function

This antibody is suited for researchers who want to investigate CXCR2 and relate it to cell-state biology. CXCR2 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

In some datasets and protocols, it is referenced by the gene symbol CD182.

Experimental Applications

Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.

Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.

Common experimental questions that benefit from target tracking include:

  • assessment of surface versus internalized pools
  • panel-based interpretation with additional lineage markers
  • activation-dependent changes across stimulation conditions

Workflow Perspective

For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.

When interpreting CXCR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

When interpreting CXCR2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

As you refine hypotheses around CXCR2, the denaturing-format format helps keep conclusions tied to preparation context.

Targets:
CXCR2
Research Area:
Cell Signaling • Developmental Biology • Immunology • Inflammation
Application:
WB
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the N-terminal extracellular region of mouse CXCR2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P25025
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 31.3% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.