Daunorubicin Hydrochloride (Daunomycin)

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Selleck Chemicals

SKU:S3035-10MG

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Daunorubicin Hydrochloride (Daunomycin) is an inhibitor of Topoisomerase and DNA/RNA Synthesis used in studies of DNA Damage Response and Apoptosis. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and dna damage / repair models.

By inhibiting Topoisomerase and DNA/RNA Synthesis, Daunorubicin Hydrochloride (Daunomycin) can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Topoisomerase and DNA/RNA Synthesis
  • Pathway perturbation studies connected to DNA Damage Response and Apoptosis
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Daunorubicin Hydrochloride (Daunomycin) is appropriate when a defined chemical perturbant is needed to connect Topoisomerase and DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Topoisomerase • DNA/RNA Synthesis
Target Class:
Enzyme
Pathways:
DNA Damage Response • Apoptosis
Research Area:
Apoptosis • Cancer • DNA Damage / Repair
CAS No.:
23541-50-6
Molecular Weight:
563.98
Formula:
C₂₇H₂₉NO₁₀·HCl
SMILES:
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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