Deferoxamine
Selleck Chemicals
SKU:S7925-1MG
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Deferoxamine is an inhibitor of HIF used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs in cancer, cell signaling, and epigenetics models.
By inhibiting HIF, Deferoxamine can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving HIF
- Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, Deferoxamine is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- HIF
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- PI3K-Akt-mTOR Signaling
- Research Area:
- Cancer • Cell Signaling • Epigenetics • Oxidative Stress
- CAS No.:
- 70-51-9
- Molecular Weight:
- 560.69
- Formula:
- C₂₅H₄₈N₆O₈
- SMILES:
- CC(=O)N(O)CCCCCN=C(O)CCC(=O)N(O)CCCCCN=C(O)CCC(=O)N(O)CCCCCN
- InChIKey:
- UBQYURCVBFRUQT-UHFFFAOYSA-N
- PubChem:
- 2973
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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