Degrasyn (WP1130)

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Selleck Chemicals

S2243-5MG

€167,00 EUR
€167,00 EUR
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Degrasyn (WP1130) is an inhibitor linked to JAK-STAT Signaling and Apoptosis and related signaling programs and related pathway-oriented research. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and caspase-associated cell-death signaling and survival decisions in angiogenesis, apoptosis, and autophagy models.

The pathway annotation connects Degrasyn (WP1130) to JAK-STAT Signaling and Apoptosis and related signaling programs, supporting experiments that monitor cytokine-responsive transcriptional signaling and immune regulation and caspase-associated cell-death signaling and survival decisions across biochemical, cellular, or phenotypic assay formats. This context is compatible with STAT phosphorylation, cytokine-response, and transcriptional assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In angiogenesis, apoptosis, and autophagy models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to JAK-STAT Signaling and Apoptosis and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in angiogenesis, apoptosis, and autophagy models
  • Combination studies with orthogonal perturbagens

Overall, Degrasyn (WP1130) is well suited to pathway-oriented studies that need a defined compound input for JAK-STAT Signaling and Apoptosis and related signaling programs readouts in angiogenesis, apoptosis, and autophagy models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
JAK-STAT Signaling • Apoptosis • Autophagy
Research Area:
Angiogenesis • Apoptosis • Autophagy • Cancer
CAS No.:
856243-80-6
Molecular Weight:
384.27
Formula:
C₁₉H₁₈BrN₃O
SMILES:
CCCC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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