Desmocollin-2 (DSC2) (Extracellular) (Human) Antibody
BiCell Scientific
SKU:00188H-50UL
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Biological Background
This antibody enables you to characterize Desmocollin-2 Extracellular with a direct, biology-first readout. Desmocollin-2 Extracellular is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol DSC2.
Use in the Laboratory
Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.
To keep datasets interpretable, labs often document:
- comparative profiling across cell states or perturbations
- changes in complex assembly with scaffold or adaptor proteins
- subcellular redistribution at contact sites versus cytoplasm
- co-localization patterns with cytoskeletal elements
Version Notes
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.
If your study spans multiple model systems, it can help to define a shared reference condition for Desmocollin-2 Extracellular so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Desmocollin-2 Extracellular patterns can be compared across experiments without guesswork.
Choose the regular format option when you want Desmocollin-2 Extracellular results aligned to your sample format.
- Targets:
- DSC2
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the N-terminal extracellular region of human Desmocollin-2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q02487
- Homology:
- Synthetic peptide sequence shows 66.7% homology to rodent sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C