Desmocollin-3 (DSC3) Antibody
BiCell Scientific
SKU:00189-50UL
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Scientific Overview
This antibody is suited for researchers who want to analyze Desmocollin-3 (DSC3) and relate it to cell-state biology. Desmocollin-3 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol DSC3.
Research Relevance
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.
When building a narrative around the target, it helps to track:
- co-localization patterns with cytoskeletal elements
- changes in complex assembly with scaffold or adaptor proteins
- comparative profiling across cell states or perturbations
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Desmocollin-3 patterns can be compared across experiments without guesswork.
For challenging targets, pairing Desmocollin-3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format variant when your project demands Desmocollin-3 (DSC3) readouts that respect preparation constraints.
- Targets:
- DSC3
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse Desmocollin-3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q14574
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 87.5% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C