Desmocollin-3 (DSC3) (Extracellular) (Human) Antibody

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BiCell Scientific

SKU:00189H-50UL

Regular price €335,00 EUR
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Size
Blocking Peptide
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About the Target

For consistent comparison across experiments, use this antibody to assess Desmocollin-3 Extracellular with a repeatable workflow. Desmocollin-3 Extracellular is a contact-site protein that shapes barrier properties and signaling at the cell surface. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.

In some datasets and protocols, it is referenced by the gene symbol DSC3.

Research Context

Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Consider these angles when interpreting target-level changes:

  • co-localization patterns with cytoskeletal elements
  • changes in complex assembly with scaffold or adaptor proteins
  • subcellular redistribution at contact sites versus cytoplasm
  • comparative profiling across cell states or perturbations

Variant Considerations

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.

If your study spans multiple model systems, it can help to define a shared reference condition for Desmocollin-3 Extracellular so cross-sample contrasts stay meaningful.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Desmocollin-3 Extracellular patterns can be compared across experiments without guesswork.

For multi-run studies, the regular format option helps keep Desmocollin-3 Extracellular trends comparable from experiment to experiment.

Targets:
DSC3
Research Area:
Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (17-aa) derived from the N-terminal extracellular region of human Desmocollin-3 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q14574
Homology:
Synthetic peptide sequence shows 76.5% homology to rodent sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.