Dicer (DICER1 or DCR1) Antibody
BiCell Scientific
SKU:51703-50UL
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About the Target
When you need to investigate Dicer (DCR1) with attention to cellular organization, this antibody provides a focused option. Dicer is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol DCR1.
Research Context
Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Dicer measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
When interpreting Dicer, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The regular format version supports deeper biological narratives around Dicer (DCR1) without overcomplicating setup.
- Targets:
- DICER1
- Research Area:
- Cell Signaling • Epigenetics
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of human Dicer protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UPY3
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C